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prostaglandin synthase We report a case of DCML deficiency a
2019-05-23

We report a case of DCML deficiency and MDS in a patient with GATA2 mutation who successfully underwent allogeneic stem cell transplantation. Case report At presentation, she had adapted to a hemoglobin level of 79g/l and had only occasional discrete symptoms of her anemia, as fatigue, other con
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br Prognosis The management of AML in the
2019-05-23

Prognosis The management of AML in the elderly patient presents a significant challenge for hematologists. Careful evaluation of both patient and disease is required in each individual case to make optimal management decisions, and maximize the benefit to the patient. Apart from the extremely old
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After overdrive pacing excitation that is one lap behind
2019-05-22

After overdrive pacing, excitation that is one lap behind (the second beat after the stimulus) is caused by several mechanisms. One is the prolonged conduction time that is longer than the TCL due to a long conduction pathway and/or slow conduction. The other is the dual-loop reentry [12]. The excit
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Interpretation Stakeholders from sectors not historically en
2019-05-22

Interpretation Stakeholders from sectors not historically engaged in health care are forming unique partnerships with common goals and a willingness to address the challenge of global cancer care. Funding None. Declaration of interests Abstract Background Since 2013 medical students from North
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br The Oct Comment by Chris Collins and
2019-05-22

The Oct 17 Comment by Chris Collins and Chris Beyrer raises several important challenges associated with strengthening country ownership and accelerating progress in the global HIV/AIDS response. Working together with our partners, the US President\'s Emergency Plan for AIDS Relief (PEPFAR) is fir
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br El Movimiento Espa ol ha
2019-05-21

El Movimiento Español 1959, ha sido definido por Eduardo Mateo Gambarte como: “el último latido de los más jóvenes exiliados por incorporarse Mouse FGF21 / Fibroblast Growth Factor 21 Protein (His Tag) la lucha antifranquista”. Pese a su limitado número de participantes y su corto recorrido, repr
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Yang et al reported PSA triggered TRUSP biopsy in Korea
2019-05-21

Yang et al. reported PSA triggered TRUSP biopsy in Korea. This study included 75 patients younger than 40 years of age, with PSA > 4.0 ng/mL; the PCa detection rate was 1.3% in the Korean study. In comparison, there were substantially more abnormal DRE findings and significant LUTS findings in our s
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corticosterone br Mechanisms of ventricular fibrillation ele
2019-05-21

Mechanisms of ventricular fibrillation/electrical storm in the Brugada syndrome patients One of the most consistent features of BrS is that premature ventricular contraction (PVC), which triggers VF, is almost always short-coupling [3,4]. An interesting phenomenon is that many of the VF episodes
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Among patients with established infection
2019-05-21

Among patients with established infection in the bone or surrounding tissue (Stage II) antibiotic penicillin-based therapy in addition to mouthwash may result in healing in patients with minor ONJ lesions. However, a large proportion of cases tend to show chronically infected necrotic process in jaw
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interleukins br Results br Discussion The results of
2019-05-21

Results Discussion The results of this retrospective study demonstrate the feasibility and safety of combined left atrial catheter ablation and Watchman® implant procedures with satisfactory LAA occlusion maintained at follow-up. The rates of successful device implantation and complete LAA occ
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br Ocular surface squamous neoplasia OSSN has emerged as
2019-05-21

Ocular surface squamous neoplasia (OSSN) has emerged as an important manifestation of the HIV epidemic, especially in sub-Saharan Africa. This region has not only gained the unenviable position of having the highest prevalence of OSSN, but patients with HIV tend to present with larger tumours and
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It is noted that in this
2019-05-20

It is noted that in this study BrS patients had an abnormality of plasma K+ concentration which has been suggested to be a potential trigger of Brugada Syndrome episodes [11]. In the absence of renal dysfunction, the hyperkalemia may result from an abnormal phenotype in BrS characterized by mutation
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By contrast the trials in India show that if
2019-05-20

By contrast, the trials in India show that if most of the target purchase SCH 527123 has no demand for sanitation then even a well-funded campaign will not succeed, and to study health effects will be pointless. The reasons for India\'s traditionally low demand for sanitation are complex, probably
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buy EPZ 005687 Introduction By catalyzing post translational
2019-05-20

Introduction By catalyzing post-translational acetylation of lysine residues, the histone acetyl transferases (HAT) CREBBP and EP300 moderate the activities of both histone and non-histone proteins. This regulates vital cellular processes such as cell cycling and apoptosis by modulating chromatin s
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The patient began CODOX M IVAC with rituximab PET
2019-05-20

The patient began CODOX-M/IVAC with rituximab [2]. PET and BM after 2 cycles showed complete remission (CR) and this was confirmed 3 and 6 months later after he completed the full treatment course. There was no delay in administration of each cycle (average: 19 days, 16–21). Eight months after thera
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