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Using characteristic features of ECM
2020-08-05

Using characteristic features of ECM proteins and a computational pipeline combining interrogation of protein and gene databases, we previously defined the matrisome as the ensemble of ECM and ECM-associated proteins [[16], [17], [18]]. In mammals, the matrisome represents 4% of the genome, or appro
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This section of the CPG document addresses the
2020-08-05

This section of the CPG document addresses the controversial issue of the possible placebo effect of PCI, indicated by the ORBITA study. The Task Force members conclude that, despite its elegant design, the ORBITA study has major limitations that make it Isochlorogenic acid C synthesis unsuitable f
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Further analysis of DDR expression using the same
2020-08-04

Further analysis of DDR1 expression using the same anti-human DDR1 antibody [19] was performed in normal human vessels (renal artery) as well as in two types of vascular disease: atherosclerosis and giant-cell arteritis (or temporal arteritis, an inflammatory condition of the blood vessels character
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Remarkably the role of Wolbachia during
2020-08-04

Remarkably, the role of Wolbachia during filarial development, molting and embryogenesis is similar to the roles attributed to these proteases in filarial development (Lustigman et al., 1992, Lustigman et al., 1996, Lustigman et al., 2004, Tort et al., 1999, Guiliano et al., 2004, Ford et al., 2009)
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It has been reported that NMDA receptor
2020-08-04

It has been reported that NMDA receptor hypofunction upregulates the expression of immediate early genes in several aldose reductase regions [39], [40]. Consistent with this finding, we demonstrated that MK-801 increased the number of c-Fos-positive cells in the PVN and PC/RS (Fig. 5). Importantly,
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Global demethylation was previously found in
2020-08-04

Global demethylation was previously found in mouse beta-lactamase ESCs under serum and leukemia inhibitory factor (LIF) (Zvetkova et al., 2005) or 2i and LIF culture (Choi et al., 2017, Ficz et al., 2013, Habibi et al., 2013, Yagi et al., 2017). We also confirmed DNA hypomethylation in diploid ESCs
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br Introduction It has become
2020-08-04

Introduction It has become increasingly apparent that seemingly identical cells in a population can actually be a heterogenous mixture differing at genome, transcriptome, and/or proteome levels. Analysis of this heterogeneity among cells within a population is critical to provide deeper understan
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Deferasirox Twin studies have shown that P has moderate heri
2020-08-04

Twin studies have shown that P has moderate heritability. Zuckerman (1989) reviewed the earlier studies of P or related traits and found a median heritability of 0.51. However, twin studies using an Eysenckian P scale have tended to estimate somewhat lower heritabilities than this, in the range 0.36
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We found that both DDR and DDR
2020-08-03

We found that both DDR1 and DDR2 ECD increased matrix mineralization as compared to native cells, with the effect of DDR2 ECD being more prominent. Both soluble (DDR2/ECD) and membrane-bound DDR2 ECD (DDR2/-KD), when compared to wild-type cells, induced larger mineral deposits. In this regard, a re
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In this modeling approach first the cross
2020-08-03

In this modeling approach, first, the cross-association volume parameter of the various mixtures of water + hydrocarbon was optimized as the only adjusting parameter of the model. Previous studies showed [59], [60] aromatics can form weak hydrogen bonds with alcohols and water, but there is not enou
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Similarly research ranking RESEARCH was not significant
2020-08-03

Similarly, research ranking (RESEARCH) was not significant in the model so H7 is not supported. Contrary to the findings of Bline et al., 2016b, Boone et al., 2006, the current study did not find an association between faculty research productivity and exam pass rate. This could be due to difference
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The relationship between the hazard function and the survivo
2020-08-03

The relationship between the hazard function and the survivor function (see more details in Allison\'s textbook [1]) is described as or as Hence, we can estimate the survival probability from the hazard function. In survival analysis, the hazard function can be represented by any probability distrib
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br Materials and methods br Results br Discussion The
2020-08-03

Materials and methods Results Discussion The availability of potent antagonists for endothelin has sparked keen interest in further developing these agents for clinical utilization. However, it continues to be a MOG (35-55) of debate and great interest as to what kind of antagonists against
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br Physiological roles of EPAC isoforms
2020-08-03

Physiological roles of EPAC isoforms: insulin secretion EPAC2 is involved in the potentiation of insulin secretion from pancreatic β Misoprostol [18] in response to incretin hormones such as glucagon-like peptide-1 (GLP-1) (Figure 2). The role of EPAC2 in these processes is to promote mobilisati
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br Discussion IR injury IRI is one of the main
2020-08-03

Discussion IR injury (IRI) is one of the main causes of cardiac failure, morbidity, and mortality after cardiac operations or LX-1031 infarctions. NO is a critical regulator of numerous processes, such as maintenance of vasomotor tone, metabolism, signal transduction, cell-to-cell interaction, a
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